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Deuterated Compounds

Deuterium, carbon-13 and nitrogen-15 labelled compounds for use as internal standards in mass spectrometry.

About deuterated compounds

Deuterated and isotope-labelled compounds are molecules in which one or more atoms have been replaced by a stable isotope, such as deuterium (d), carbon-13 (13C) or nitrogen-15 (15N). The Cadulac catalogue lists labelled versions of many well-known pharmaceutical substances, for example Warfarin-d5, Simvastatin-d6, Valsartan-d9 and Trimethoprim-d3.

Because labelled compounds behave almost identically to their unlabelled parent during sample preparation and chromatography, yet can be told apart by mass, they are widely used as internal standards. This makes quantitative results more consistent and helps correct for matrix effects and sample losses.

The number in a product name, such as -d4 or -d10, indicates how many deuterium atoms are present. Searching our catalogue by parent name will often show the labelled version, the unlabelled API and related impurities together.

Professional applications

Common professional uses include internal standards for LC-MS/MS and GC-MS quantification, bioanalytical method development and validation, pharmacokinetic and drug metabolism research, environmental and residue analysis, and clinical research laboratory workflows.

Labelled metabolites and labelled impurities are also valuable in research that tracks how a compound changes in biological or environmental systems.

How to enquire

Every order with Cadulac Chemicals Ltd begins with a direct enquiry. Send us the exact product name, the CAS registry number, the quantity you need and a short description of the intended professional application. Our team will confirm availability, packaging options, supply timelines and the technical information that can be provided for the specific batch and supply route.

We do not publish fixed purity values, stock positions or certificates on listing pages, because these details can vary between batches and suppliers. Instead, everything is confirmed in writing upon enquiry so that your procurement and quality teams can review the information before an order is placed. Buyers remain responsible for confirming suitability, safe handling, storage and compliance with all applicable laws and institutional procedures.

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Frequently asked questions

What does the 'd' number mean?

It shows how many hydrogen atoms have been replaced with deuterium, for example -d5 means five deuterium atoms.

Can you confirm isotopic enrichment?

Technical information such as isotopic enrichment may be available depending on the product and supply route, and is confirmed upon enquiry.